Article

Understanding natural selection in Holocene Europe using multi-locus genotype identity scans

2023-04-25

Abstract excerpt

Ancient DNA (aDNA) has been a revolutionary technology in understanding human history but has not been used extensively to study natural selection as large sample sizes to study allele frequency changes over time have thus far not been available. Here, we examined a time transect of 708 published samples over the past 7,000 years of European history using multi-locus genotype-based selection scans. As aDNA data is...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c7ffccb7-1534-57e9-b523-fb34462a9d41
DOI: 10.1101/2023.04.24.538113

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Understanding natural selection in Holocene Europe using multi-locus genotype identity scansDOI 10.1101/2023.04.24.538113Read

Leveraging ancient DNA to uncover signals of natural selection in Europe lost due to admixture or drift.Semantic proximity Read

Global patterns of natural selection inferred using ancient DNASemantic proximity Read

Pervasive findings of directional selection realize the promise of ancient DNA to elucidate human adaptationSemantic proximity Read

Ancient DNA reveals that few GWAS loci have been strongly selected during recent human historySemantic proximity Read

A catalog of ancient proxies for modern genetic variantsSemantic proximity Read

Deep estimation of the intensity and timing of selection from ancient genomesSemantic proximity Read

Deep estimation of the intensity and timing of natural selection from ancient genomes.Semantic proximity Read

Ancient DNA reveals pervasive directional selection across West Eurasia.Semantic proximity Read

1,000 ancient genomes uncover 10,000 years of natural selection in EuropeSemantic proximity Read

Admixture has obscured signals of historical hard sweeps in humansSemantic proximity Read

Genome-wide scans for footprints of natural selection.Semantic proximity Read

Direct detection of natural selection in Bronze Age BritainSemantic proximity Read