Mutation ages and population origins inferred from genomes in structured populations

Abstract excerpt

Inferring the time of origin (age) of mutations is an old question in population genetics and inferring their population of origin has become of particular interest with the sequencing of the Neanderthal genome. However, existing methods to infer mutation ages and populations of origin do not explicitly consider population structure, migration rates, and divergence times, which may bias estimates, and it is unclea...

Topics

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• China
• Evolution, Molecular
• Genetics, Population
• Genome, Human
• Models, Genetic
• Mutation Rate
• Polymorphism, Single Nucleotide
• Skin Pigmentation

Identifiers and source

Literature Corpus work

bb2f42ec-f833-5a79-a2d7-52de189ee494

DOI

10.1101/2025.01.28.635333