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Article

Dating rare mutations from small samples with dense marker data.

Genetics - 1 Aug 2014

Gandolfo Luke C, Bahlo Melanie, Speed Terence P

Abstract excerpt

We present a method for estimating the age of a mutation based on the genetic length of ancestral haplotypes shared between individuals carrying the mutation. The method can be reliably applied to small samples, typical of situations involving rare mutations, and makes effective use of modern high-density SNP data, thus overcoming two of the limitations with existing methods. The method provides age estimates and...

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Identifiers

PMID: 24879464
DOI: 10.1534/genetics.114.164616
PMCID: PMC4125402

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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