Article

Live cell imaging of ATP levels reveals metabolic compartmentalization within motoneurons and early metabolic changes in <i>FUS</i> ALS motoneurons

2023-03-24

Abstract excerpt

Motoneurons are one of the highest energy demanding cell types and a primary target in Amyotrophic lateral sclerosis (ALS), a debilitating and lethal neurodegenerative disorder without currently available effective treatments. Disruption of mitochondrial ultra-structure, transport and metabolism is a commonly reported phenotype in ALS models and can critically affect survival and proper function of motor neurons....

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Literature Corpus work: 3f0d49c6-5631-570b-8eed-514c01b3ebc8
DOI: 10.1101/2023.03.22.533787

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Live cell imaging of ATP levels reveals metabolic compartmentalization within motoneurons and early metabolic changes in <i>FUS</i> ALS motoneuronsDOI 10.1101/2023.03.22.533787Read

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