Article

Association between the Methylation of CpG Islands in JAK-STAT Pathway-Related Genes and Colorectal Cancer

2020-07-30

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: The Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway is involved in a series of biological processes. Aberrant promoter methylation of CpG islands plays an important role in carcinogenesis. However, the association between the DNA methylation of JAK-STAT pathway-related genes in peripheral blood leukocytes and colorectal cancer (C...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3ef56acc-d837-5f55-83b7-9e35aac1b52f
DOI: 10.21203/rs.3.rs-49979/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Association between the Methylation of CpG Islands in JAK-STAT Pathway-Related Genes and Colorectal CancerDOI 10.21203/rs.3.rs-49979/v1Read

Association between the methylation of the STAT1 and SOCS3 in peripheral blood and gastric cancer.Semantic proximity Read

Multiple gene-specific DNA methylation in blood leukocytes and colorectal cancer risk: a case-control study in ChinaSemantic proximity Read

STAT3 Expression, Molecular Features, Inflammation Patterns, and Prognosis in a Database of 724 Colorectal CancersSemantic proximity Read

Abnormal genetic and epigenetic changes in signal transducer and activator of transcription 4 in the pathogenesis of inflammatory bowel diseases.Semantic proximity Read

Hypermethylation associated with inactivation of the SOCS-1 gene, a JAK/STAT inhibitor, in human hepatoblastomasSemantic proximity Read

SCTR hypermethylation is a diagnostic biomarker in colorectal cancerSemantic proximity Read

JAK/STAT/SOCS-signaling pathway and colon and rectal cancer.Semantic proximity Read

DNA methylation regulates constitutive expression of Stat6 regulatory genes SOCS-1 and SHP-1 in colon cancer cells.Semantic proximity Read

Methylation Status of Transcriptional Modulatory Genes Associated with Colorectal Cancer in Northeast ChinaSemantic proximity Read

Genetic variants in IL-6/JAK/STAT3 pathway and the risk of CRC.Semantic proximity Read

Methylation status of SOCS1 and SOCS3 genes in patients with acute lymphoid leukemia: A case-control studySemantic proximity Read

Kras gene mutation and RASSF1A, FHIT and MGMT gene promoter hypermethylation: indicators of tumor staging and metastasis in adenocarcinomatous sporadic colorectal cancer in Indian population.Semantic proximity Read