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Article

Genetic variants in IL-6/JAK/STAT3 pathway and the risk of CRC.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 May 2016

Wang Shuwei, Zhang Weidong

Abstract excerpt

Interleukin (IL)-6 and the downstream Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway have previously been reported to be important in the development of colorectal cancer (CRC), and several studies have shown the relationship between the polymorphisms of related genes in this pathway with the risk of CRC. However, the findings of these related studies are inconsistent....

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Source

Identifiers

PMID: 26638167
DOI: 10.1007/s13277-015-4529-1

Genes

STAT3
JAK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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