Article

Methylation status of SOCS1 and SOCS3 genes in patients with acute lymphoid leukemia: A case-control study

2024-01-31

Abstract excerpt

<h4>Objective: </h4> Acute Lymphoid Leukemia (ALL) is the leading childhood cancer with high mortality and morbidity. Studies have suggested an association of epigenetic transformations with prognosis, recurrence, and immunophenotypes of ALL. SOCS1 and SOCS3 are tumor suppressors inhibiting JAK/STAT signaling pathway and the resultant aberrant cell proliferation. We aimed to assess the methylated status of these g...

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Literature Corpus work: 5646bda9-c386-56e3-a77c-4f216caf0f35
DOI: 10.22541/au.170670624.42377352/v1

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