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Article

Hypermethylation associated with inactivation of the SOCS-1 gene, a JAK/STAT inhibitor, in human hepatoblastomas

1 Feb 2003

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 12601549
DOI: 10.1007/s100380300008

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Hypermethylation associated with inactivation of the SOCS-1 gene, a JAK/STAT inhibitor, in human hepatoblastomasPMID 12601549Read ↗

SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activitySemantic proximity Read ↗

Hypermethylation-associated Inactivation of the SOCS-1 Gene, a JAK/STAT Inhibitor, in Human Pancreatic CancersSemantic proximity Read ↗

Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinomaSemantic proximity Read ↗

Combined hypermethylation and chromosome loss associated with inactivation of SSI-1/SOCS-1/JAB gene in human hepatocellular carcinomasSemantic proximity Read ↗

Hypermethylation of suppressor of cytokine signaling 1 in hepatocellular carcinoma patients.Semantic proximity Read ↗

Constitutional activation of IL-6-mediated JAK/STAT pathway through hypermethylation of SOCS-1 in human gastric cancer cell lineSemantic proximity Read ↗

Association between the Methylation of CpG Islands in JAK-STAT Pathway-Related Genes and Colorectal CancerSemantic proximity Read ↗

SOCS1 Is a Suppressor of Liver Fibrosis and Hepatitis-induced CarcinogenesisSemantic proximity Read ↗

Methylation status of SOCS1 and SOCS3 genes in patients with acute lymphoid leukemia: A case-control studySemantic proximity Read ↗

SOCS3 genetic variants and promoter hypermethylation in patients with chronic hepatitis B.Semantic proximity Read ↗

Suppressor of cytokine signalling‐1 gene silencing in acute myeloid leukaemia and human haematopoietic cell linesSemantic proximity Read ↗

SOCS-3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancerSemantic proximity Read ↗

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