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MipSScs: Artificial neural network-based data integration of 2D/3D single-cell spatial RNA sequence data from virus-infected human cerebral organoids

2026-06-11

Abstract excerpt

<h4>ABSTRACT</h4> There is interest in the use of recent single-cell spatial transcriptomic technologies to gain biological insights into disease mechanisms. Previously, we characterized the use of herpes simplex virus 1 (HSV-1) induced neuroinflammation in 2D dissociated cells from human cerebral organoids (dcOrgs) to model molecular and transcriptomic readouts associated with Alzheimer’s disease (AD). In this w...

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Literature Corpus work: 3ef103c6-c721-5304-a114-a81e2f6f4f48
DOI: 10.64898/2026.06.08.727881

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