Article

Cell Type Specific Inference of Perturbations in Synaptic Communication with MultiNeuronChat

2025-11-12

Abstract excerpt

Inference of differential neuron-neuron and neuron-glia communication from single nucleus RNA sequencing data is a powerful technique to uncover altered communication pathways when comparing groups, such as disease and control, developmental stages, or age groups, or different treatments. Yet, the communication changes are typically not identified on the cell type pair level, limiting its resolution in terms of an...

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Literature Corpus work: 4c626538-8880-5ef7-ba53-f2f3d6be2f78
DOI: 10.1101/2025.11.11.687822

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