Article

Modeling Organoid Population Electrophysiology Dynamics

2025-03-02

Abstract excerpt

<h4>ABSTRACT</h4> Improving models to investigate neurodegenerative disease, neurodevelopmental disease, neuro-toxicology and neuropharmacology is critical to improve our basic understanding of the human nervous system, as well as to accelerate discovery of interventions and drugs. Improved models of the human central nervous system could enable critical discoveries related to functional changes induced by sensor...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5f1c1402-ff48-534f-9a19-dfacf09559b6
DOI: 10.1101/2025.03.02.641081

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Modeling Organoid Population Electrophysiology DynamicsDOI 10.1101/2025.03.02.641081Read

Human brain organoid networksSemantic proximity Read

Variability vs Phenotype: multimodal analysis of Dravet Syndrome Brain Organoids powered by Deep LearningSemantic proximity Read

Identification of neural oscillations and epileptiform changes in human brain organoidsSemantic proximity Read

MEA-NAP compares microscale functional connectivity, topology, and network dynamics in organoid or monolayer neuronal culturesSemantic proximity Read

Human Neural Organoid Microphysiological Systems Show the Building Blocks Necessary for Basic Learning and MemorySemantic proximity Read

Patient-derived Brain Organoids Reveal Divergent Neuronal Activity Across Subpopulations of Autism Spectrum DisorderSemantic proximity Read

Long-Term Maintenance of Human Stem Cell-derived Neural Networks for Electrophysiology StudiesSemantic proximity Read

Data-driven burst shape analysis for functional phenotyping of neuronal culturesSemantic proximity Read

High-density extracellular recordings from the interior of intact brain organoids enable automated high-throughput functional assaySemantic proximity Read

Functional Cell-Type Identification in Neuronal Networks Using High-Density Microelectrode ArraysSemantic proximity Read

In vitro reconstitution of hippocampal cell assembliesSemantic proximity Read

Electrophysiological development and functional plasticity in dissociated human cerebral organoids across multiple cell linesSemantic proximity Read