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Article

Cerebral organoids for modeling of HSV-1-induced-multiscale neuropathology associated with Alzheimer’s disease and phenotypic rescue

2022-02-13

Abstract excerpt

<h4>ABSTRACT</h4> Herpes simplex virus type I (HSV-1) infection is a potential risk factor involved in the pathogenesis of Alzheimer’s disease (AD) and contributes to the AD viral hypothesis. However, further understanding of the neuropathological effects of the HSV-1 infection is hampered by the limitations of existing infection models due to the distinct differences between human brains and other mammalians’ br...

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Literature Corpus work
9441c516-c8a4-57b7-899f-75eea31525ca
DOI
10.1101/2022.02.11.480178
Open publication

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Cerebral organoids for modeling of HSV-1-induced-multiscale neuropathology associated with Alzheimer’s disease and phenotypic rescueDOI 10.1101/2022.02.11.480178
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