Article

VAPOR: A variational autoencoder with transport operators to disentangle cellular gene expression dynamics of co-occurring biological processes in time and space

2024-10-29

Abstract excerpt

Abstract Single-cell and spatial transcriptomics enable the analysis of cellular states and dynamics in gene expression, revealing how diverse biological processes relate to these states over time and space. To study these dynamics, trajectory inference methods order cells along computationally inferred paths to reconstruct gradual transitions in cell states. However, by encouraging smooth and continuous trajector...

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Literature Corpus work: 4a439af6-6db4-51c9-ac68-344ffc9690d1
DOI: 10.1101/2024.10.27.620534

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VAPOR: A variational autoencoder with transport operators to disentangle cellular gene expression dynamics of co-occurring biological processes in time and spaceDOI 10.1101/2024.10.27.620534Read

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