Article

Cell type-specific and disease-associated eQTL in the human lung

2023-03-21

Abstract excerpt

Common genetic variants confer substantial risk for chronic lung diseases, including pulmonary fibrosis (PF). Defining the genetic control of gene expression in a cell-type-specific and context-dependent manner is critical for understanding the mechanisms through which genetic variation influences complex traits and disease pathobiology. To this end, we performed single-cell RNA-sequencing of lung tissue from 67 P...

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Literature Corpus work: 612b0c7f-3586-573e-9ac8-b8b380710955
DOI: 10.1101/2023.03.17.533161

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