Article

Peripheral positioning of lysosomes supports melanoma aggressiveness

2023-07-09

Abstract excerpt

Emerging evidences suggest that function and position of organelles are pivotal for tumor cell dissemination. Among them, lysosomes stand out as they integrate metabolic sensing with gene regulation and secretion of proteases. Yet, how their function is linked to their position and how this controls metastasis remains elusive. Here, we analyzed lysosome subcellular distribution in patient-derived melanoma cells an...

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Literature Corpus work: 3e6c5151-f244-592c-99bd-4be153ca84e6
DOI: 10.1101/2023.07.07.548108

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