Article

Highly conserved sequence-specific DNA binding networks of 716 transcription factors associated with continuing divergent genomic evolution of human and chimpanzee brain development.

2024-11-15

Abstract excerpt

<title>Abstract</title> <p>Emergence during mammalian evolution of common and divergent traits of genomic regulatory networks (GRNs) encompassing ubiquitous, compositionally nearly identical yet quantitatively distinct panels of DNA sequences of transcription factor binding sites (TFBS) for 716 proteins is reported. The evolutionary-conserved foundation of these GRNs appears assembled from arrays of DNA codes for...

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Literature Corpus work: 3e5cd89a-c9d6-5bf9-b229-5396ffe685d2
DOI: 10.21203/rs.3.rs-5442388/v1

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