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Advances in understanding immune homeostasis in latent tuberculosis infection

13 Feb 2024

Abstract excerpt

Nearly one-fourth of the global population is infected by Mycobacterium tuberculosis (Mtb), and approximately 90%-95% remain asymptomatic as latent tuberculosis infection (LTBI), an estimated 5%-10% of those with latent infections will eventually progress to active tuberculosis (ATB). Although it is widely accepted that LTBI transitioning to ATB results from a disruption of host immune balance and a weakening of...

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PMID: 38351551
DOI: 10.1002/wsbm.1643

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