Article

Spatio-molecular gene expression reflects dorsal anterior cingulate cortex structure and function in the human brain

2025-07-17

Abstract excerpt

In the human brain, the dorsal anterior cingulate cortex (dACC) plays key roles in various components of cognitive control, and is particularly relevant for reward processing and conflict monitoring. The dACC regulates expression of fear and pain, and its dysfunction is implicated in a number of neuropsychiatric disorders. Compared to more recently specialized neocortical areas, such as the dorsolateral prefrontal...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3de77849-3b25-556e-923d-2fcc9ec27692
DOI: 10.1101/2025.07.14.664821

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Spatio-molecular gene expression reflects dorsal anterior cingulate cortex structure and function in the human brainDOI 10.1101/2025.07.14.664821Read

Integrated single cell and unsupervised spatial transcriptomic analysis defines molecular anatomy of the human dorsolateral prefrontal cortexSemantic proximity Read

Cross-species Multimodal Single-cell Profiling of Dorsal and Ventral Prefrontal Cortex Reveals Cell-type Divergence and PTSD-associated Regulatory LandscapesSemantic proximity Read

Molecular signatures of cognition and affectSemantic proximity Read

Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortexSemantic proximity Read

Deep transcriptome sequencing of subgenual anterior cingulate cortex reveals disorder-specific expression changes in major psychiatric disordersSemantic proximity Read

Integrating spatial transcriptomics and snRNA-seq data enhances differential gene expression analysis results of AD-related phenotypesSemantic proximity Read

Coexpression network architecture reveals the brain-wide and multiregional basis of disease susceptibility.Semantic proximity Read

A Population-scale Single-cell Spatial Transcriptomic Atlas of the Human CortexSemantic proximity Read

Structural and cellular transcriptome foundations of human brain diseaseSemantic proximity Read

Multiregion Cross-species Single-cell Multimodal Study of Prefrontal Cortex Reveals Cell-type Divergence and PTSD-associated Regulatory LandscapesSemantic proximity Read

An integrated single-nucleus and spatial transcriptomics atlas reveals the molecular landscape of the human hippocampusSemantic proximity Read

The transcriptomic architecture of the human cerebral cortexSemantic proximity Read