Article

Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex

2020-02-28

Abstract excerpt

We used the 10x Genomics Visium platform to define the spatial topography of gene expression in the six-layered human dorsolateral prefrontal cortex (DLPFC). We identified extensive layer-enriched expression signatures, and refined associations to previous laminar markers. We overlaid our laminar expression signatures onto large-scale single nuclei RNA sequencing data, enhancing spatial annotation of expression-dr...

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Literature Corpus work: 89a21fe5-7183-5340-986d-41078347a88e
DOI: 10.1101/2020.02.28.969931

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