Article

Deep transcriptome sequencing of subgenual anterior cingulate cortex reveals disorder-specific expression changes in major psychiatric disorders

2019-04-05

Abstract excerpt

<h4>ABSTRACT</h4> How do differences in onset, symptoms, and treatment response arise between various mental illnesses despite substantial overlap of genetic risk factors? To address this question, we carried out deep RNA sequencing of human postmortem subgenual anterior cingulate cortex, a key component of limbic circuits linked to mental illness. Samples were obtained from 200 individuals diagnosed with bipolar...

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Literature Corpus work: 12f74f66-fac8-57c0-9392-2a2574fab159
DOI: 10.1101/598649

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