Article

<i>Plasmodium</i> circumsporozoites targeted by RFdiffusion / cyclic-peptides

2025-09-01

Abstract excerpt

The surface-exposed circumsporozoite-protein (CSP) of blood-migrating Plasmodium falciparum , is the target for preventive vaccines inducing 70-80 % protection against human malaria. Rather than for prevention, therapeutic-like peptides computationally designed to recognize full-length CSP were generated here aiming to complement the present vaccines. To generate thousands of lineal-peptide backbones and amino ac...

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Literature Corpus work: 3db6d3ff-42ca-5f02-8a2a-265a0cd4fc75
DOI: 10.1101/2025.09.01.673429

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