Article

Role of a versatile peptide motif in controlling Hox nuclear export and autophagy in the <i>Drosophila</i> fat body

2019-11-15

Abstract excerpt

Hox proteins are major regulators of embryonic development, acting in the nucleus to regulate the expression of their numerous downstream target genes. By analyzing deleted forms of the Drosophila Hox protein Ultrabithorax (Ubx), we revealed the presence of an unconventional Nuclear Export Signal (NES) that overlaps with the highly conserved hexapeptide (HX) motif. This short linear motif was originally described...

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Literature Corpus work: 3d9e470a-dc16-5875-828a-0d06500c47c7
DOI: 10.1101/843383

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