Article
Pleiotropic functions of a conserved insect-specific Hox peptide motif.
Development (Cambridge, England) - 1 Dec 2005
Hittinger Chris Todd, Stern David L, Carroll Sean B
Abstract excerpt
The proteins that regulate developmental processes in animals have generally been well conserved during evolution. A few cases are known where protein activities have functionally evolved. These rare examples raise the issue of how highly conserved regulatory proteins with many roles evolve new functions while maintaining old functions. We have investigated this by analyzing the function of the ;QA' peptide motif...
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