Article

Highly expressed STING in liver metastasis of uveal melanoma can lead to synergistic killing

2026-08-20

Abstract excerpt

<title>Abstract</title> <p>BRCA1-assocoiated protein 1 (BAP1) is frequently mutated in metastatic uveal melanoma (MUM). Since BAP1 loss of function was previously linked to changes of expression of Stimulator of Interferon Genes (STING), a DNA damage and viral DNA sensor, the expression of STING protein was examined by immunohistochemistry. It was discovered that the MUM cancer cells expressed high level of STING...

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Literature Corpus work: 3d9e23a9-6088-5a4f-bcf5-41dfae1af21b
DOI: 10.21203/rs.3.rs-10293742/v1

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