Article
Structural Elucidation of β<sub>1</sub>- and β<sub>2</sub>-Transferrin Using Microprobe-Capture In-Emitter Elution and High-Resolution Mass Spectrometry
2023-01-30
Abstract excerpt
<h4>Background</h4> Cerebrospinal fluid (CSF) leak is typically diagnosed by detecting a protein marker β 2 -transferrin (β 2 -Tf) in secretion samples. β 2 -Tf and β 1 -transferrin (β 1 -Tf) are glycoforms of human transferrin (Tf). A novel affinity capture technique for sample preparation, called microprobe-capture in-emitter elution (MPIE), was incorporated with high-resolution mass spectrometry (HR-MS) to anal...
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Identifiers and source
- Literature Corpus work
- 3d9c50d1-2dc2-5758-a186-428004bd128e
- DOI
- 10.1101/2023.01.29.23285161
