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Integrated top-down and bottom-up mass spectrometry enables precise characterization of proteoforms and their post-translational modifications within the protein corona

2025-09-16

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<title>Abstract</title> <p>Precise characterization of proteins and proteoforms within the protein corona is essential for developing safer and more effective nanomedicines for diagnostic and therapeutic applications. Although the protein corona phenomenon has been recognized in nanomedicine for nearly two decades, the application of top-down proteomics to analyze proteoforms within this context has only recently...

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Literature Corpus work
e15fbc4a-9ab7-5d5d-bab2-2e758a993c8e
DOI
10.21203/rs.3.rs-7593385/v1
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Integrated top-down and bottom-up mass spectrometry enables precise characterization of proteoforms and their post-translational modifications within the protein coronaDOI 10.21203/rs.3.rs-7593385/v1
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