Article

Multicenter Evaluation of Label-Free Quantification in Human Plasma: Benchmarking with a High Dynamic Range Multispecies Sample Set

2024-12-19

Abstract excerpt

<title>Abstract</title> <p>Human plasma is routinely collected during clinical care and constitutes a rich source of biomarkers for diagnostics and patient stratification. Liquid chromatography-mass spectrometry (LC-MS)-based proteomics is a key method for plasma biomarker discovery, but the high dynamic range of plasma proteins poses significant challenges for MS analysis and data processing. To benchmark the qu...

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Literature Corpus work: b7a8741a-9ffa-56b1-a2ae-cb165c80c6bf
DOI: 10.21203/rs.3.rs-5618718/v1

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