Article

Metabolic adaption to extracellular pyruvate triggers biofilm formation in <i>Clostridioides difficile</i>

2021-01-23

Abstract excerpt

Clostridioides difficile infections are associated with gut microbiome dysbiosis and are the leading cause of hospital acquired diarrhoea. The infectious process is strongly influenced by the microbiota and successful infection relies on the absence of specific microbiota-produced metabolites. Deoxycholic acid (DOC) and short chain fatty acids are microbiota-produced metabolites that limit the growth of C. diffic...

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Literature Corpus work: 3d91fd9e-b4a2-5161-8643-17b20faaa2a6
DOI: 10.1101/2021.01.23.427917

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