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Clostridioides difficile -mucus interactions encompass shifts in gene expression, metabolism, and biofilm formation

5 Jun 2024

Abstract excerpt

ABSTRACT In a healthy colon, the stratified mucus layer serves as a crucial innate immune barrier to protect the epithelium from microbes. Mucins are complex glycoproteins that serve as a nutrient source for resident microflora and can be exploited by pathogens. We aimed to understand how the intestinal pathogen, Clostridioides difficile , independently uses or manipulates mucus to its benefit, without...

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Clostridium difficile and Clostridium perfringens research
Gut microbiota and health
Helicobacter pylori-related gastroenterology studies

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38837404
DOI: 10.1128/msphere.00081-24

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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