Article
Ectoine Globally Hypomethylates DNA in Skin Cells and Suppresses Cancer Proliferation
2023-08-07
Abstract excerpt
Epigenetic modifications, mainly aberrant DNA methylation, have been shown to silence the ex-pression of genes involved in epigenetic diseases, including cancer suppression genes. Almost all conventional cancer therapeutic agents, such as the DNA hypomethylation drug, 5-aza-2-deoxycytidine, have insurmountable side effects. To investigate the role of ectoine in skin cell DNA methylation and cancer cell proliferati...
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Identifiers and source
- Literature Corpus work
- 3d7e7c62-f609-5f61-8f33-066545ebc3a4
- DOI
- 10.20944/preprints202308.0461.v1
