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Identification of dihydromyricetin as a natural DNA methylation inhibitor with rejuvenating activity in human skin

4 Mar 2024

Abstract excerpt

Changes in DNA methylation patterning have been reported to be a key hallmark of aged human skin. The altered DNA methylation patterns are correlated with deregulated gene expression and impaired tissue functionality, leading to the well-known skin aging phenotype. Searching for small molecules, which correct the aged methylation pattern therefore represents a novel and attractive strategy for the identification...

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Identifiers

PMID: 38500495
DOI: 10.3389/fragi.2023.1258184

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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