Article

Sequence diversity in the 3’ untranslated region of alphavirus modulates IFIT2-dependent restriction in a cell type-dependent manner

2021-12-11

Abstract excerpt

<h4>ABSTRACT</h4> Alphaviruses (family Togaviridae ) are a diverse group of positive-sense RNA (+ssRNA) viruses that are transmitted by arthropods and are the causative agent of several significant human and veterinary diseases. Interferon (IFN)-induced proteins with tetratricopeptide repeats (IFITs) are a family of RNA-binding IFN stimulated genes (ISGs) that are highly upregulated following viral infection, an...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3d7dcb1c-6b1e-59e9-bbbd-d95a96e6395d
DOI: 10.1101/2021.12.10.472177

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Sequence diversity in the 3’ untranslated region of alphavirus modulates IFIT2-dependent restriction in a cell type-dependent mannerDOI 10.1101/2021.12.10.472177Read

Sequence Diversity in the 3' Untranslated Region of Alphavirus Modulates IFIT2-Dependent Restriction in a Cell Type-Dependent Manner.Semantic proximity Read

IFIT1 Differentially Interferes with Translation and Replication of Alphavirus Genomes and Promotes Induction of Type I Interferon.Semantic proximity Read

Interferon inhibits a model RNA virus via a limited set of inducible effector genesSemantic proximity Read

A viral RNA structural element alters host recognition of nonself RNA.Semantic proximity Read

TRIM69 inhibits Vesicular Stomatitis Indiana Virus (VSIV)Semantic proximity Read

IFIT1 is rapidly evolving and exhibits disparate antiviral activities across 11 mammalian ordersSemantic proximity Read

The transcriptional landscape of Venezuelan equine encephalitis virus (TC-83) infectionSemantic proximity Read

IFIT3 RNA-binding activity promotes influenza A virus infection and translation efficiencySemantic proximity Read

Translational Control of Alphavirus–Host Interactions: Implications in Viral Evolution, Tropism and Antiviral ResponseSemantic proximity Read

RNA structures within Venezuelan equine encephalitis virus E1 alter macrophage replication fitness and contribute to viral emergenceSemantic proximity Read

IFIT3 RNA-binding activity promotes influenza A virus infection and translation efficiencySemantic proximity Read

Host cell restriction factors of equine infectious anemia virusSemantic proximity Read