Article

Impact of baseline culture conditions of mouse-derived cancer organoids when determining therapeutic response and tumor heterogeneity

2021-10-14

Abstract excerpt

Representative models are needed to screen new therapies for patients with cancer. Cancer organoids are a leap forward as a culture model that faithfully represents the disease. Mouse-derived cancer organoids (MDCOs) are becoming increasingly popular, however there has yet to be a standardized method to assess therapeutic response and identify subpopulation heterogeneity. There are multiple factors unique to organ...

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Literature Corpus work: 3cf9a31e-2a06-5ade-ad85-96e40a96adca
DOI: 10.1101/2021.10.12.464087

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