Article

Unravelling the shared genetic mechanisms underlying 18 autoimmune diseases using a systems approach

2021-03-29

Abstract excerpt

Autoimmune diseases (AiDs) are complex heterogeneous diseases characterized by hyperactive immune responses against self. Genome-wide association studies have identified thousands of single nucleotide polymorphisms (SNPs) associated with several AiDs. While these studies have identified a handful of pleiotropic loci that confer risk to multiple AiDs, they lack the power to detect shared genetic factors residing ou...

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Literature Corpus work: 3ce0fbc9-6c13-5173-9a2e-99b67c4a2afa
DOI: 10.1101/2021.03.28.437437

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