Article

The proto CpG island methylator phenotype of sessile serrated adenomas/polyps

2018-06-27

Abstract excerpt

Sessile serrated adenomas/polyps (SSA/Ps) are the putative precursors of the ˜20% of colon cancers with the CpG island methylator phenotype (CIMP), but their molecular features are poorly understood. We used high-throughput analysis of DNA methylation and gene expression to investigate the epigenetic phenotype of SSA/Ps. Fresh-tissue samples of 17 SSA/Ps and (for comparison purposes) 15 conventional adenomas (cADN...

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Literature Corpus work: 3cb7040e-debe-5ffa-9119-87aea5fc3df5
DOI: 10.1101/357178

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