Article
Endoscopic and molecular characterization of colorectal sessile serrated adenoma/polyps with cytologic dysplasia.
Gastrointestinal endoscopy - 1 Dec 2017
Tanaka Yoshihito, Yamano Hiro-O, Yamamoto Eiichiro, Matushita Hiro-O, Aoki Hironori, Yoshikawa Kenjiro, Takagi Ryo, Harada Eiji, Nakaoka Michiko, Yoshida Yuko, Eizuka Makoto, Sugai Tamotsu, Suzuki Hiromu, Nakase Hiroshi
Abstract excerpt
BACKGROUND AND AIMS: Sessile serrated adenoma/polyps (SSA/Ps), which are precursor lesions of colorectal cancer (CRC) with BRAF mutation and the CpG island methylator phenotype (CIMP), develop cytologic dysplasia (CD) during the progression of colorectal tumorigenesis. In the present study we aimed to clarify the endoscopic and molecular signatures of SSA/Ps, with and without CD. METHODS: A series of 208 serrated...
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