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Gene Signature in Sessile Serrated Polyps Identifies Colon Cancer Subtype

29 Mar 2016

Abstract excerpt

Sessile serrated colon adenoma/polyps (SSA/P) are found during routine screening colonoscopy and may account for 20% to 30% of colon cancers. However, differentiating SSA/Ps from hyperplastic polyps (HP) with little risk of cancer is challenging and complementary molecular markers are needed. In addition, the molecular mechanisms of colon cancer development from SSA/Ps are poorly understood. RNA sequencing...

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PMID: 27026680
DOI: 10.1158/1940-6207.capr-15-0363

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