Article

Assessing the importance of resistance, persistence and hyper-mutation for antibiotic treatment success with stochastic modelling

2022-04-09

Abstract excerpt

Antimicrobial resistance poses a rising threat to global health, making it crucial to understand the routes of bacterial survival during antimicrobial treatments. Treatment failure can result from genetic or phenotypic mechanisms, which diminish the effect of antibiotics. By assembling empirical data, we find that, for example, Pseudomonas aeruginosa infections in cystic fibrosis patients frequently contain persi...

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Literature Corpus work: 3ca57154-c7b9-5e89-b785-256a68d36d54
DOI: 10.1101/2022.04.07.487440

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