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Article

Persistence: a copacetic and parsimonious hypothesis for the existence of non-inherited resistance to antibiotics.

Current opinion in microbiology - 1 Oct 2014

Levin Bruce R, Concepción-Acevedo Jeniffer, Udekwu Klas I

Abstract excerpt

We postulate that phenotypic resistance to antibiotics, persistence, is not an evolved (selected-for) character but rather like mutation, an inadvertent product of different kinds of errors and glitches. The rate of generation of these errors is augmented by exposure to these drugs. The genes that have been identified as contributing to the production of persisters are analogous to the so-called mutator genes;...

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Identifiers

PMID: 25090240
DOI: 10.1016/j.mib.2014.06.016
PMCID: PMC4253300

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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