Article

Leveraging the Genetic Correlation between Traits Improves the Detection of Epistasis in Genome-wide Association Studies

2022-12-01

Abstract excerpt

Epistasis, commonly defined as the interaction between genetic loci, is known to play an important role in the phenotypic variation of complex traits. As a result, many statistical methods have been developed to identify genetic variants that are involved in epistasis, and nearly all of these approaches carry out this task by focusing on analyzing one trait at a time. Previous studies have shown that jointly model...

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Literature Corpus work: 3ca522fb-4f67-557e-b592-5e27cd8ee3ed
DOI: 10.1101/2022.11.30.518547

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