Back to search

Article

Clonal <i>Parabacteroides</i> from Gut Microfistulous Tracts as Transmissible Cytotoxic Succinate-Commensal Model of Crohn’s Disease Complications

2024-01-10

Abstract excerpt

Crohn’s disease (CD) has been traditionally viewed as a chronic inflammatory disease that cause gut wall thickening and complications, including fistulas, by mechanisms not understood. By focusing on Parabacteroides distasonis (presumed modern succinate-producing commensal probiotic), recovered from intestinal microfistulous tracts (cavernous fistulous micropathologies CavFT proposed as intermediate between ‘muco...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a9a2b0d7-524b-516e-8422-ce6e1f614925
DOI
10.1101/2024.01.09.574896
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Clonal <i>Parabacteroides</i> from Gut Microfistulous Tracts as Transmissible Cytotoxic Succinate-Commensal Model of Crohn’s Disease ComplicationsDOI 10.1101/2024.01.09.574896
Mesenteric adipose tissue-derived Klebsiella variicola disrupts intestinal barrier and promotes colitis by type VI secretion systemSemantic proximity
Live <i>Malassezia</i> strains isolated from the mucosa of patients with ulcerative colitisSemantic proximity
A polymicrobial view of disease potential in Crohn's-associated adherent-invasive E. coli.Semantic proximity
A tale of two habitats: Bacteroides fragilis, a lethal pathogen and resident in the human gastrointestinal microbiomeSemantic proximity
Characterization of fungal and bacterial Dysbiosis in Crohn's Disease Patients with Intestinal FibrosisSemantic proximity
Translocation of Viable Gut Microbiota to Mesenteric Adipose Drives Formation of Creeping Fat in Humans.Semantic proximity
<i>Faecalibacterium prausnitzii</i> induces an anti-inflammatory response and a metabolic reprogramming in human monocytesSemantic proximity
The Genus Alistipes: Gut Bacteria With Emerging Implications to Inflammation, Cancer, and Mental HealthSemantic proximity
Gut protective <i>Klebsiella</i> species promotes microbiota recovery and pathobiont clearance while preventing inflammationSemantic proximity
Complete Genome Sequence of a Parabacteroides distasonis Strain (CavFT hAR46) Isolated from a Gut Wall-Cavitating Microlesion in a Patient with Severe Crohn’s DiseaseSemantic proximity
A consortia of clinical E. coli strains with distinct in-vitro adherent/invasive properties establish their own co-colonization niche and shape the intestinal microbiota in inflammation-susceptible miceSemantic proximity
The Keystone commensal bacterium Christensenella minuta DSM 22607 displays anti-inflammatory properties both in vitro and in vivoSemantic proximity
Select a neighboring publication to make it the new centre.