Article

Gut Dysbiosis with a Pathobiont Shifts the Intestinal Microbiota Profile and Accelerates Lupus Nephritis

2020-10-12

Abstract excerpt

<h4>ABSTRACT</h4> The gut microbiota (GM) exerts a strong influence over the host immune system and dysbiosis of this microbial community can affect the clinical phenotype in chronic inflammatory conditions. To explore the role of the GM in lupus nephritis, we colonized NZM2410 mice with Segmented Filamentous Bacteria (SFB). Gut colonization with SFB was associated with worsening glomerulonephritis, glomerular an...

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Literature Corpus work: e944cfe8-6a7c-5e10-be47-164adeeceadd
DOI: 10.1101/2020.10.12.310763

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