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Article

rvTWAS: identifying gene-trait association using sequences by utilizing transcriptome-directed feature selection.

Genetics - 7 Feb 2024

He Jingni, Li Qing, Zhang Qingrun

Abstract excerpt

Toward the identification of genetic basis of complex traits, transcriptome-wide association study (TWAS) is successful in integrating transcriptome data. However, TWAS is only applicable for common variants, excluding rare variants in exome or whole-genome sequences. This is partly because of the inherent limitation of TWAS protocols that rely on predicting gene expressions. Our previous research has revealed...

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PMID: 38001381
DOI: 10.1093/genetics/iyad204

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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