Article

Long-read sequencing reveals the RNA isoform repertoire of neuropsychiatric risk genes in human brain

2024-02-23

Abstract excerpt

Neuropsychiatric disorders are highly complex conditions and the risk of developing a disorder has been tied to hundreds of genomic variants that alter the expression and/or products (isoforms) made by risk genes. However, how these genes contribute to disease risk and onset through altered expression and RNA splicing is not well understood. Combining our new bioinformatic pipeline IsoLamp with nanopore long-read...

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Literature Corpus work: 29bfc8e0-fbd1-5f34-ad44-c242d4f81254
DOI: 10.1101/2024.02.22.24303189

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