Article

Functional phenotyping of genomic variants using multiomic scDNA-scRNA-seq

2024-06-01

Abstract excerpt

Genomic variation ranging from single nucleotide polymorphisms to structural variants can impact gene function and expression, contributing to disease mechanisms such as cancer progression. The systematic study of this variation is hindered by inefficient precision editing tools making it challenging to confidently link genotype and gene expression in pooled screens. Additionally, assessing heterogenous variants i...

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Literature Corpus work: 3c6fc095-c7e5-5d63-b9ac-fe90b32d67e7
DOI: 10.1101/2024.05.31.596895

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