Article

High-throughput targeted long-read single cell sequencing reveals the clonal and transcriptional landscape of lymphocytes

2018-09-24

Abstract excerpt

High-throughput single-cell RNA-Sequencing is a powerful technique for gene expression profiling of complex and heterogeneous cellular populations such as the immune system. However, these methods only provide short-read sequence from one end of a cDNA template, making them poorly suited to the investigation of gene-regulatory events such as mRNA splicing, adaptive immune responses or somatic genome evolution. To...

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Literature Corpus work: 554558bc-3bea-5bbf-a9da-911888214bec
DOI: 10.1101/424945

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