Article

DRP1-mediated mitochondrial fission is essential to maintain cristae morphology and bioenergetics

2022-01-03

Abstract excerpt

Mitochondria and peroxisomes are both dynamic signaling organelles that constantly undergo fission. While mitochondrial fission is known to coordinate cellular metabolism, proliferation, and apoptosis, the physiological relevance of peroxisome dynamics and the implications for cell fate are not fully understood. DRP1 (dynamin-related protein 1) is an essential GTPase that executes both mitochondrial and peroxisoma...

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Literature Corpus work: 3c60d6e5-1abf-5d22-929a-e34ede7338e1
DOI: 10.1101/2021.12.31.474637

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