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Homozygous haplotype deficiency in Manech Tête Rousse dairy sheep revealed a nonsense variant in <i>MMUT</i> gene affecting newborn lamb viability

2023-03-11

Abstract excerpt

Recessive deleterious variants are known to segregate in livestock populations as in human, and some may cause lethality when homozygous. By scanning the genome of 6,845 Manech Tête Rousse dairy sheep using phased 50k SNP genotypes and pedigree data, we searched for deficiency in homozygous haplotype (DHH). Five Manech Tête Rousse deficient homozygous haplotypes (MTRDHH1 to 5) were identified with a homozygous def...

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Literature Corpus work
3c1d4536-9de8-548e-898e-d12a10c69c96
DOI
10.1101/2023.03.10.531894
Open publication

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Homozygous haplotype deficiency in Manech Tête Rousse dairy sheep revealed a nonsense variant in <i>MMUT</i> gene affecting newborn lamb viabilityDOI 10.1101/2023.03.10.531894
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