Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Nonsense Variant in CCDC65 Gene Causes Respiratory Failure Associated with Increased Lamb Mortality in French Lacaune Dairy Sheep.

Genes - 24 Dec 2021

Ben Braiek Maxime, Moreno-Romieux Carole, Allain Charlotte, Bardou Philippe, Bordes Arnaud, Debat Frédéric, Drögemüller Cord, Plisson-Petit Florence, Portes David, Sarry Julien, Tadi Némuel, Woloszyn Florent, Fabre Stéphane

Abstract excerpt

We recently demonstrated that the Lacaune deficient homozygous haplotype 6 (LDHH6) potentially hosts a recessive perinatal lethal mutation in Lacaune dairy sheep mapped on OAR3. In the present study, we have analyzed the whole-genome sequences of two Lacaune ram heterozygous carriers of LDHH6. After variant calling and filtering against the variants of 86 non-carrier rams, we have identified a single nucleotide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Codon, Nonsense
Share to Glycoproteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to Phenotype

Share to Respiratory Insufficiency

Source

Open in PubMed Open full text

Identifiers

PMID: 35052387
DOI: 10.3390/genes13010045
PMCID: PMC8774411

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Nonsense Variant in CCDC65 Gene Causes Respiratory Failure Associated with Increased Lamb Mortality in French Lacaune Dairy Sheep.PMID 35052387Read ↗

Identification of homozygous haplotypes carrying putative recessive lethal mutations that compromise fertility traits in French Lacaune dairy sheep.Semantic proximity Read ↗

Searching for homozygous haplotype deficiency in Manech Tête Rousse dairy sheep revealed a nonsense variant in the MMUT gene affecting newborn lamb viability.Semantic proximity Read ↗

Homozygous haplotype deficiency in Manech Tête Rousse dairy sheep revealed a nonsense variant in <i>MMUT</i> gene affecting newborn lamb viabilitySemantic proximity Read ↗

A single base pair duplication in <i>SLC33A1</i> gene causes fetal losses and neonatal lethality in Manech Tête Rousse dairy sheepSemantic proximity Read ↗

A novel nonsense mutation in the DMP1 gene identified by a genome-wide association study is responsible for inherited rickets in Corriedale sheep.Semantic proximity Read ↗

An initiator codon mutation in SDE2 causes recessive embryonic lethality in Holstein cattle.Semantic proximity Read ↗

A missense mutation in AGTPBP1 was identified in sheep with a lower motor neuron disease.Semantic proximity Read ↗

UNRAVELING CLN7 disease: the distinct roles of two close MFSD8/CLN7 splice variants in phenotypic expressionSemantic proximity Read ↗

Clinical findings and prevalence of the mutation associated with primary ciliary dyskinesia in Old English Sheepdogs.Semantic proximity Read ↗

Golden Retriever dogs with neuronal ceroid lipofuscinosis have a two-base-pair deletion and frameshift in CLN5Semantic proximity Read ↗

Identification of a nonsense mutation in CWC15 associated with decreased reproductive efficiency in Jersey cattle.Semantic proximity Read ↗

A comparative FISH mapping of LCA5L gene in cattle, sheep, and goats.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.