Article
Runs of homozygosity reveal signatures of positive selection for reproduction traits in breed and non-breed horses.
BMC genomics - 9 Oct 2015
Metzger Julia, Karwath Matthias, Tonda Raul, Beltran Sergi, Águeda Lídia, Gut Marta, Gut Ivo Glynne, Distl Ottmar
Abstract excerpt
BACKGROUND: Modern horses represent heterogeneous populations specifically selected for appearance and performance. Genomic regions under high selective pressure show characteristic runs of homozygosity (ROH) which represent a low genetic diversity. This study aims at detecting the number and functional distribution of ROHs in different horse populations using next generation sequencing data. METHODS: Next...
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